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Uso do Baclofeno no Tratamento da Dependência do Álcool

Experiência profissionalizante na vertente de Farmácia Comunitária, Farmácia Hospitalar e Investigação
Authors: Rodrigues, Ana Isabel Carvalho;

Uso do Baclofeno no Tratamento da Dependência do Álcool

Abstract

O presente relatório faz parte da unidade curricular “Estágio” do Mestrado Integrado em Ciências Farmacêuticas e está dividido em três partes. O álcool é uma substância psicoativa que quando consumida em excesso pode causar dependência e problemas com grande impacto negativo na saúde pública. A dependência do álcool é considerada uma doença que possui uma grande carga global a nível social e económico. No entanto, não existem muitos tratamentos para esta dependência e os que existem nem sempre têm a taxa de sucesso desejada. Assim, no primeiro capítulo deste documento é abordado o uso off label de um fármaco, o baclofeno, nesta dependência. Neste sentido, foram desenvolvidos, ao longo de vários anos, uma grande quantidade de estudos com o objetivo de avaliar a eficácia deste fármaco, onde os resultados encontrados serão descritos neste relatório de estágio. No segundo capítulo é descrito o estágio realizado nos serviços farmacêuticos do Centro Hospitalar Universitário da Cova da Beira, na Covilhã, que se iniciou no dia 21 de Janeiro e decorreu até ao dia 8 de Março de 2019. Nesta parte, encontra-se descrita a experiência e os conhecimentos adquiridos nas diversas áreas dos serviços farmacêuticos hospitalares. O terceiro capítulo diz respeito ao estágio realizado na farmácia comunitária que se iniciou no dia 11 de Março e terminou no dia 31 de Maio de 2019, na Farmácia Gastromil, em Viseu. Nesta parte, está descrita toda a experiência e conhecimentos adquiridos na área de farmácia comunitária.

The present report is part of the “Internship” curricular unit of the Integrated Master Degree in Pharmaceutical Sciences, and is divided into three chapters. The first chapter describes the research aspect concerning the use of baclofen in alcohol dependence situations. Alcohol is a psychoactive substance, and when consumed in excess can cause addiction and problems with a huge negative impact on public health. Alcohol dependence is considered a disease with a high overall social and economic burden. However, there are not many treatments for this dependency, and those that exist do not always have the desired success rate. In this chapter, the off label use of baclofen will be discussed as possible treatment in alcohol dependence. In this sense, a large number of studies were developed over several years with the objective of evaluating the efficacy of this drug, in which the results will be described. The second chapter describes the internship carried out in the pharmaceutical services of the University Hospital Center of Cova da Beira, in Covilhã, which began on January 21 and lasted until March 8, 2019. In this part, the experience and all the knowledge acquired in the various areas of hospital pharmaceutical services are described. The third chapter concerns the internship held at the community pharmacy that started on March 11 and ended on May 31, 2019 at the Gastromil Pharmacy in Viseu. This part describes all the experience and knowledge acquired in the area of community pharmacy.

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Portugal
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Keywords

Álcool, Farmácia Hospitalar, Tratamento, Baclofeno, Farmácia Comunitária, Domínio/Área Científica::Ciências Médicas::Ciências da Saúde::Ciências Farmacêuticas, Dependência

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selected citations
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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