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Álcool e Miocardiopatia Dilatada

Authors: Esteves, Adriana Carones;

Álcool e Miocardiopatia Dilatada

Abstract

O consumo de álcool é um hábito muito difundido nas mais diferentes sociedades e culturas. O efeito do seu consumo na saúde cardiovascular depende tanto do padrão como da quantidade consumida. Apesar do consumo excessivo ser frequentemente associado a outcomes clínicos negativos, como doenças cardiovasculares e hipertensão arterial, verifica-se que o seu consumo moderado se traduz em benefícios para a saúde cardiovascular. A miocardiopatia dilatada é a miocardiopatia mais prevalente em todo o mundo, sendo a causa mais frequente de transplante cardíaco e a terceira maior causa de insuficiência cardíaca. A miocardiopatia alcoólica é um tipo específico de miocardiopatia dilatada que ocorre perante um consumo crónico excessivo de álcool. Assim como a miocardiopatia dilatada, a miocardiopatia alcoólica é caracterizada por uma dilatação e disfunção sistólica do ventrículo esquerdo. Habitualmente esta patologia apresenta-se em homens, mais frequentemente, entre os 35 e 60 anos de idade. O seu diagnóstico depende da história de consumo crónico excessivo de álcool em associação a uma série de alterações celulares, histológicas e estruturais do miocárdio. A presente monografia compreende uma revisão bibliográfica sobre o efeito do consumo do álcool na mortalidade global e cardiovascular, hipertensão arterial e insuficiência cardíaca. É explorada a relação entre o consumo de álcool e o surgimento da miocardiopatia alcoólica, assim como uma descrição dos seus aspetos epidemiológicos, mecanismos associados à lesão do miocárdio, clínica, diagnóstico e tratamento.

Alcohol consumption is a widespread habit in many different societies and cultures. The effect of its consumption on cardiovascular health depends on both the consumption pattern and the amount consumed. Although excessive consumption is often associated with negative clinical outcomes, such as cardiovascular diseases and arterial hypertension, it’s observed that moderate consumption turns out to be benefic for cardiovascular health. Dilated cardiomyopathy is the most prevalent cardiomyopathy in the world, being the most frequent cause of cardiac transplantation and the third largest cause of heart failure. Alcoholic cardiomyopathy is a specific type of dilated cardiomyopathy that occurs with excessive chronic alcohol consumption. Like dilated cardiomyopathies, alcoholic cardiomyopathy is characterized by dilation and systolic dysfunction of the left ventricle. Usually this pathology occurs in men, most often between 35 and 60 years of age. Its diagnosis depends on the history of excessive chronic alcohol consumption in association with a series of cellular, histological and structural changes of the myocardium. The present monograph is a literature review on the effect of alcohol consumption on cardiovascular and global mortality, arterial hypertension and heart failure. The relationship between alcohol consumption and the onset of alcoholic cardiomyopathy is explored, as well as a description of its epidemiological aspects, mechanisms associated with myocardial injury, clinical diagnosis and treatment.

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Portugal
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Keywords

Domínio/Área Científica::Ciências Médicas::Ciências da Saúde::Medicina, Consumo de Álcool, Miocardiopatia, Miocardiopatia Alcoólica

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selected citations
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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