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Master thesis . 2022
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Estudo piloto de tripanossomose em cães na região da Ponta do Ouro e Machangulo, Moçambique

Authors: Rossini, Sarah Marina;

Estudo piloto de tripanossomose em cães na região da Ponta do Ouro e Machangulo, Moçambique

Abstract

ABSTRACT - PILOT STUDY OF TRYPANOSOMOSIS IN DOGS IN THE REGION OF PONTA DO OURO AND MACHANGULO, MOZAMBIQUE - Trypanosomosis is a disease caused by trypanosomes, flagellate protozoa transmitted by flies of the genus Glossina spp., commonly called Tsetse flies. The geographic distribution of Trypanosomosis is mainly reported in sub-Saharan Africa, affecting humans causing human African Trypanosomosis (“Sleeping Sickness”), and animals causing African Animal Trypanosomosis (“Nagana”). African Animal Trypanosomosis mainly affects domestic ruminants, causing severe impact on their health, well-being and productivity. However, dogs are also very susceptible to infection, mainly by Trypanosoma congolense, and they may develop canine Trypanosomosis. The scarcity of data concerning the frequency of Canine Trypanosomosis, disease presentations and severity, as well as on the distribution of vector insects, reinforces the need and importance of research and investment. During the dog sterilization and vaccination campaigns, carried out by the Vets on the Road Association, in the areas of Ponta do Ouro and Machangulo, 109 blood samples were collected, of which 48 (44.0%) in Ponta do Ouro and 61 (56.0%) in Machangulo. Molecular diagnosis of Trypanosoma congolese was performed at the Biotechnology Centre of the Eduardo Mondlane University in Maputo. Only one positive case was detected in Machangulo, a peninsula in southwestern Mozambique. This finding confirms the occurrence of canine Trypanosomosis in Mozambique, but in a very low frequency (0.92%). However, this result must be validated by future studies, based upon representative samples, to assess disease impact on the health and well-being of the dog population of Mozambique.

A Tripanossomose é uma doença causada por tripanossoma, protozoários flagelados transmitidos por moscas pertencentes ao género Glossina spp., vulgarmente chamadas moscas Tsé-Tsé. A distribuição geográfica da Tripanossomose observa-se sobretudo na África subsaariana, onde afeta quer humanos, causando Tripanossomose Africana Humana (“Doença do Sono”), quer animais, causando Tripanossomose Animal Africana (“Nagana”). A Tripanossomose Animal Africana atinge principalmente ruminantes domésticos, causando um impacto grave na sua produção, saúde e bem-estar. No entanto, os cães também são muito suscetíveis à infeção, sendo principalmente afetados pela espécie Trypanosoma congolense, desenvolvendo Tripanossomose Canina. A escassez de dados relativos à distribuição de insetos vetores, à prevalência e à taxa de mortalidade induzida pela doença, reforça a necessidade e a importância de investigação e investimento. Durante as campanhas de esterilização e de vacinação antirrábica de cães, realizadas pela Associação Vets on the Road, nas áreas de Ponta do Ouro e de Machangulo, foram recolhidas 109 amostras de sangue, das quais 48 (44,0%) na Ponta do Ouro e 61 (56,0%) em Machangulo. O diagnóstico molecular de Trypanosoma congolense foi feito no Centro de Biotecnologia da Universidade Eduardo Mondlane, Maputo. Foi detetado apenas um caso positivo em Machangulo, uma península no sudoeste de Moçambique. Este resultado confirma a ocorrência de Tripanossomose Canina em Moçambique, mas numa frequência muito baixa (0,92%) que deve ser validada por estudos futuros, baseados em amostras representativas da população, para avaliar o impacto da doença na saúde e no bem-estar dos cães em Moçambique.

Dissertação de Mestrado Integrado em Medicina Veterinária

N/A

Country
Portugal
Keywords

Tripanossomose canina, Moçambique, Trypanosoma congolense, Glossina spp., Canine Trypanosomosis, Mozambique

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selected citations
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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