The Global Ocean is the cornerstone of our planet's life support system. It encompasses one of four Global Commons, the High Seas, and represents the sum of all seas and oceans that are interconnected at a global scale. Although considered as a unique piece of the planet system, it consists on multiple and complex components, regulated autonomously but interacting with each other. Ocean Governance is a topic that, while not new, is still far from consensual in the way it is conceptualized and implemented. Although the United Nations Convention on the Law of the Sea (UNCLOS), recognized by a large number of States as "the Constitution for the Oceans", determines its spatial configuration and regulates the components of the Ocean, this is not achieved globally, resulting in gaps in terms of spatial coverage of this single element - the Global Ocean. Considering the theme’s complexity and the interdependence of the maritime areas’ regimes pursuant the Convention, this paper highlights some of the major constraints and challenges regarding to Global Ocean Governance to be faced in the years to come. Among others, issues as the legitimacy of the governance process in the global scene, the tragedy of the global commons and the evolution of the oceans’ regime, will be considered to set the major emerging challenges in this proposed topic.