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Article . 2010
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Repositório do Centro Hospitalar de Lisboa Central, EPE
Article . 2010
Data sources: Repositório do Centro Hospitalar de Lisboa Central, EPE
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Hipersensibilidade à varfarina: que abordagem?

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2010 Portugal English Publisher:Ordem dos MédicosJournal:Acta Médica Portuguesa (issn: 0870-399X, Copyright policy )
Authors: Lima, AF; Reis, J; Serrano, F; Borges, A;

handle: 10400.17/711

Hipersensibilidade à varfarina: que abordagem?

Abstract

The authors report a clinical case of warfarin hypersensitivity noticed when a patient, with thromboembolic risk, was submitted to warfarin. She was found to be heterozigotic to -1639G>A (gene VKORC1) and homozygotic to 1075A>C (genotype CYP2C9*3/*3). In this article the warfarin pharmacodinamics and its role over Vitamin K is revisited. It includes some suggested indications for investigating genetic polymorphisms, in order to avoid complications associated with warfarin.

Country
Portugal
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Keywords

Varfarina, Medicine (General), R5-920, MAC MED MAF, R, Medicine, Efeitos Adversos, Anticoagulantes, Hipersensibilidade

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selected citations
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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