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Doctoral thesis . 2016
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Comportamiento clínico-epidemiológico de la obesidad en el estudio de prevalencia del síndrome metabólico de la ciudad de Maracaibo: influencia de los fenotipos metabólicos sobre el punto de corte de la circunferencia abdominal

Authors: Bermúdez Pirela, Valmore José;

Comportamiento clínico-epidemiológico de la obesidad en el estudio de prevalencia del síndrome metabólico de la ciudad de Maracaibo: influencia de los fenotipos metabólicos sobre el punto de corte de la circunferencia abdominal

Abstract

Introducción y Objetivos: La obesidad es un grave problema de salud pública en la mayoría de las sociedades con estilos de vida occidentalizados. En Venezuela, son pocos los estudios que han abordado la epidemiología de la obesidad y ninguno que haya determinado los puntos de corte de circunferencia abdominal para nuestra localidad. Por esto, el objetivo del presente estudio fue diseñar un estudio clínico-epidemiológico que permitió establecer el comportamiento epidemiológico del SM y sus componentes individuales, incluyendo la obesidad, así como la determinación de los puntos de corte para la circunferencia abdominal. Resultados: La prevalencia de obesidad según el IMC para ambos sexos y todos los grupos etarios fue del 33,3% (n=701) mientras que la prevalencia de sobrepeso fue del 34,8% (n=733). La prevalencia de obesidad abdominal usando los puntos de corte sugeridos IDF/AHA/NHLBI/IASO/ADA y los sugeridos por el ATPIII fueron del 74,2% y del 51,7% respectivamente. En relación con el cálculo de los puntos de corte para nuestra población, las mejores variables metabólicas predictivas para la obtención de clústers de individuos sanos metabólicamente ó enfermos fueron en conjunto: HOMA2-IR, HOMA2-βcell y Triacilglicéridos los puntos de corte para circunferencia abdominal tanto para hombres como para mujeres fue de 98,15 cm y 91,5 cm, respectivamente. Conclusiones: La prevalencia de obesidad en la Ciudad de Maracaibo es elevada, equiparable a la de países como los EUA. Este problema se acentúa si se toma en cuenta el número de individuos con obesidad abdominal según los puntos de corte considerados como clásicos. Sin embargo, dicha prevalencia se reduce drásticamente a un 35% al utilizar los puntos de corte propuestos por este estudio.

Introduction and objectives: Obesity is a serious public health problem in most westernized societies. In Venezuela, few studies have addressed the epidemiology of obesity even less those who have undertaken waist circumference cut-off points for our city. In this sense, the objective of this study was to design a clinical-epidemiological trial with multistage random sampling design in order to establish the epidemiological behavior of the MS and its individual components, including obesity, as well as determining the cut-off points for abdominal circumference. Results: obesity prevalence according to BMI for both sexes and all age groups was 33.3% (n=701) and the overweight prevalence was 34.8% (n=733). The prevalence of abdominal obesity using the cut-offs suggested by IDF/AHA/NHLBI/IASO/ADA-2009 and those suggested by the ATPIII were 74.2% and 51.7% respectively. In relation to WC cutoffs calculation, the best metabolic overall predictors’ variables for clusters formation were: HOMA2-IR, HOMA2-βcell and triglycerides (TAG). The cut-off for WC was 98.15 cm and 91.5 cm, for men and women respectively. Conclusions: The prevalence of obesity according to BMI in the city of Maracaibo is high, comparable to that of countries like the US. This problem is accentuated taking into account the number of individuals with abdominal obesity, since the prevalence individuals with a high-risk waist circumference doubles the number of obese people by diagnosed by BMI. The cut-off points for our population in this study (Male: 98.15 cm and Women: 91.5 cm) is shown to be in an intermediate point between those suggested by the recent harmonization of criteria for SM and those suggested by the ATP III.

Country
Spain
Related Organizations
Keywords

Síndrome metabólico, Obesidad, Maracaibo (Venezuela), Índice de masa corporal (IMC)

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
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