
The toxic, carcinogenic and mutagenic effects of N-nitroso compounds are briefly discussed with reference to recent reviews. These adverse biological effects are discussed in relation to the necessity of metabolic activation by microsomal enzymes for the nitrosamins but not for the nitrosamides.
Nitrosamines, Esophageal Neoplasms, Liver Neoplasms, Methylnitrosourea, Amides, Kidney Neoplasms, Respiratory Tract Neoplasms, Pregnancy Complications, Structure-Activity Relationship, Teratogens, Pregnancy, Microsomes, Carcinogens, Animals, Humans, Female, Gastrointestinal Neoplasms, Mutagens, Nitroso Compounds
Nitrosamines, Esophageal Neoplasms, Liver Neoplasms, Methylnitrosourea, Amides, Kidney Neoplasms, Respiratory Tract Neoplasms, Pregnancy Complications, Structure-Activity Relationship, Teratogens, Pregnancy, Microsomes, Carcinogens, Animals, Humans, Female, Gastrointestinal Neoplasms, Mutagens, Nitroso Compounds
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