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Engenharia de tecidos para regeneração do tecido nervoso: retrospetiva e perspetivas futuras

Authors: Borlido, Ângela Fernandes Gomes;

Engenharia de tecidos para regeneração do tecido nervoso: retrospetiva e perspetivas futuras

Abstract

A Engenharia de Tecidos é o ramo da Engenharia que se preocupa no desenvolvimento de metodologias e estratégias para a reparação, regeneração e substituição de tecidos e órgãos lesados. A regeneração do tecido nervoso é um fenómeno biológico complexo. Pois, o Sistema Nervoso Periférico regenera-se sensivelmente no seu ambiente promissor, enquanto que o Sistema Nervoso Central, mais concretamente na medula espinal não se regenera sensivelmente no seu ambiente nativo. Este trabalho consiste numa pesquisa bibliográfica da Engenharia de Tecidos aplicada ao tecido nervoso, incluindo assim, as metodologias alcançadas até ao momento na regeneração deste tecido. No entanto, a aplicabilidade clínica ainda não é significativa, de maneira, que a investigação a este nível continua a ser bastante promissora. The Tissue Engineering is the branch of engineering that is concerned in the development of methodologies and strategies for the repair, regeneration and replacement of damaged tissues and organs. The nerve tissue regeneration is a complex biological phenomenon. The Peripheral Nervous System regenerates substantially in its promising environment, while the Central Nervous System, in particular in the spinal cord, does not regenerate substantially in its native environment. This work consists of a literature research of tissue engineering applied to the nerve tissue, including the methodologies achieved so far in the regeneration of this tissue. However, the clinical applicability is still not significant, so that research on this level is still very promising.

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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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