Powered by OpenAIRE graph
Found an issue? Give us feedback
addClaim

Meningites bacterianas

Authors: Pereira, Diana Nogueira;

Meningites bacterianas

Abstract

A meningite é um processo inflamatório que envolve as meninges, o encéfalo e a medula espinal; pode ser causada por diversos microrganismos, como vírus, fungos e bactérias. A meningite bacteriana representa um problema de Saúde Pública devido à alta incidência principalmente em crianças, com elevadas taxas de letalidade e sequelas. Trata-se de uma emergência médica, que requer diagnóstico e tratamento imediato. Streptococcus pneumoniae, Haemophilus influenza e Neisseria meningitidis são os mais comuns, e também os mais agressivos patógenos da meningite. Se, no passado a história natural de meningite bacteriana encerrava um prognóstico reservado, com uma mortalidade muito elevada, com o advento da antibioterapia, houve uma alteração muito significativa. A antibioterapia empírica inicial é efetuada com base na etiologia provável de acordo com a idade; actualmente as cefalosporinas de 3ª geração, ceftriaxona ou cefotaxima, constituem a terapêutica de eleição. Nos últimos anos com o aparecimento de novas vacinas, ocorreu uma mudança drástica na epidemiologia desta patologia representando uma nova esperança no controlo desta infeção. Contudo, e apesar de todos os estudos até hoje realizados é necessário um conhecimento ainda mais profundo desta patologia, bem como das técnicas de diagnóstico, desenvolvimento de novos antibióticos e vacinas, de modo a que as taxas de mortalidade a as sequelas associadas sejam ínfimas. Meningitis is an inflammation that involves the meninges, the brain and the spinal cord; can be caused by various microorganisms such as viruses, fungi and bacteria. Represent a public health problem due to the high incidence especially in children with high rates of mortality and sequelae. This is a medical emergency that requires immediate diagnosis and treatment. Streptococcus pneumoniae, Haemophilus influenzae and Neisseria meningitidis are most common and also the most aggressive pathogens of meningitis. If in the past the natural history of bacterial meningitis led to a poor prognosis, with a very high mortality, with the advent of antibiotics, there was a very significant change. The initial empirical antibiotic treatment is carried out based on probable etiology according to age; currently the 3rd generation cephalosporins, ceftriaxone or cefotaxime, are the preferred therapy. In recent years with the emergence of new vaccines, there has been a drastic change in the epidemiology of this disease represents a new hope in controlling this infection. However, despite all studies to date an even deeper understanding of this disease, as well as diagnostic techniques, development of new antibiotics and vaccines made is required, so that the mortality rates associated sequelae are negligible.

Country
Portugal
Related Organizations
  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    0
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
    OpenAIRE UsageCounts
    Usage byUsageCounts
    visibility views 134
    download downloads 2K
  • 134
    views
    2K
    downloads
    Powered byOpenAIRE UsageCounts
Powered by OpenAIRE graph
Found an issue? Give us feedback
visibility
download
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
views
OpenAIRE UsageCountsViews provided by UsageCounts
downloads
OpenAIRE UsageCountsDownloads provided by UsageCounts
0
Average
Average
Average
134
2K
Upload OA version
Are you the author of this publication? Upload your Open Access version to Zenodo!
It’s fast and easy, just two clicks!