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Two different groups, using ChIP-seq data, have recently published the genome-wide distribution of histones H3.1 and H3.3 in Arabidopsis thaliana. In one report, Stroud and colleagues determined that, whereas H3.1 was enriched in repetitive pericentromeric and silent chromatin, H3.3 was enriched in transcriptionally active regions. This work was performed using seedlings, which contained dividing and non-dividing cells. In a second report, Wollmann and colleagues found similar results analyzing dividing or non-dividing tissue. None of these reports addressed the analysis of telomeres or centromeres. Our group has recently described an experimental approach that allows the study of the epigenetic status of some Arabidopsis repetitive sequences by analyzing ChIP-seq data. By using this approach and the data generated by Stroud, Wollmann and colleagues, we found that telomeres are enriched in H3.3 with regard to the centromeric 178 bp repeats, whereas the centromeric repeats are enriched in H3.1 with regard to telomeres.
Histones, Base Sequence, Transcription, Genetic, Centromere, Arabidopsis, Genetic Variation, Telomere, Article, Chromatin, Repetitive Sequences, Nucleic Acid
Histones, Base Sequence, Transcription, Genetic, Centromere, Arabidopsis, Genetic Variation, Telomere, Article, Chromatin, Repetitive Sequences, Nucleic Acid
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