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Inflammatory and immune response genes have significantly altered expression in schizophrenia

descriptionPublicationkeyboard_double_arrow_right Article 20 Nov 2012 Spain, United Kingdom English Publisher:Springer Science and Business Media LLCJournal:Molecular Psychiatry, volume 18, pages 1,056-1,057 (issn: 1359-4184, eissn: 1476-5578, Copyright policy )
Authors: Sainz, J.; Mata, I.; Barrera, J.; Perez-Iglesias, R.; Varela, I.; Arranz, M.J.; Rodriguez, M.C.; +1 Authors

doi: 10.1038/mp.2012.165

pmid: 23164819

handle: 10261/78751

Inflammatory and immune response genes have significantly altered expression in schizophrenia

Abstract

We analyzed the blood transcriptome of 36 drug naive schizophrenia patients and 40 healthy matched controls by next-generation sequencing. Among the 22 278 genes analyzed, we found significant differential expression (P-value adjusted <0.05) in 200 genes.

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Keywords

Adult, Inflammation, Wound Healing, Models, Genetic, Genes, MHC Class II, Models, Neurological, Real-Time Polymerase Chain Reaction, Gene Expression Regulation, Schizophrenia, Humans, RNA, Messenger, Transcriptome, Sequence Alignment, Genetic Association Studies

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selected citations
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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