Human TSG101 does not replaceSaccharomyces cerevisiaeVPS23 role in the quality control of plasma membrane proteins

descriptionPublicationkeyboard_double_arrow_right Article 01 Apr 2003 Spain English Publisher:Oxford University Press (OUP)Journal:FEMS Microbiology Letters, volume 221, pages 151-154 (issn: 0378-1097, eissn: 1574-6968,

Copyright policy )

Authors: Blanco, Sandra; Lazo, Pedro A.;

doi: 10.1016/s0378-1097(03)00179-4

pmid: 12725919

handle: 10261/7084

Human TSG101 does not replaceSaccharomyces cerevisiaeVPS23 role in the quality control of plasma membrane proteins

- Summary
- Subjects
- Metrics

Abstract

The Saccharomyces cerevisiae VPS23 (STP22) gene is implicated in the control of vesicle movement and quality of plasma membrane proteins. VPS23 mutants have defects either in removing defective membrane proteins such as alpha-mating factor receptor and arginine permease. The human ortholog TSG101 and its variants, isolated from tumor cells, do not substitute VPS23 in its ability to rescue the phenotype of defective plasma membrane proteins.

Country

Spain

Related Organizations

Spanish National Research Council
Spain
University of Salamanca
Spain
Centro de Investigación del Cáncer
Spain

Keywords

Saccharomyces cerevisiae Proteins, Endosomal Sorting Complexes Required for Transport, Cell Membrane, Genetic Complementation Test, Vesicular Transport Proteins, Gene Expression, Membrane Proteins, Membrane Transport Proteins, Saccharomyces cerevisiae, Arginine, DNA-Binding Proteins, TSG101, Tsg101 Protein, Humans, Carrier Proteins, Mating Factor, Peptides, Plasmids, Transcription Factors

Impact byBIP!

	selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	3
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average