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Polimorfo de maleato de paroxetina y formulaciones farmacéuticas que lo contienen

Authors: Stampa Díez del Corral, Alberto; Bosch, Jordi; Molins, Elies; Onrubia Miguel, M.ª del Carmen;

Polimorfo de maleato de paroxetina y formulaciones farmacéuticas que lo contienen

Abstract

El nuevo polimorfo de maleato de paroxetina, Forma B presenta una estabilidad química sensiblemente más elevada que la Forma A de maleato de paroxetina conocida anteriormente. Esta superior estabilidad permite la utilización del nuevo polimorfo para la fabricación de medicamentos para el tratamiento de trastornos relacionados con disfunciones del sistema nervioso central y, consecuentemente, la obtención de nuevas formulaciones farmacéuticas que contiene dicho maleato de paroxetina en Forma B. Se describe también una utilización y un procedimiento de obtención de este maleato de paroxetina en Forma B.

Referencia OEPM: P9801426.-- Fecha de solicitud: 07/07/1998.-- Titular: Medichem S.A.

Peer reviewed

Keywords

Estabilidad, Maleato de paroxetina, Sistema nervioso central, Polimorfos, Medicamentos, Antidepresivos

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selected citations
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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