Modified oligonucleotides as regulators of gene expression

[EN] The invention relates to a compound of pARNi and a group R, where R is selected from alkyl, cycloalkyl, heterocycloalkyl, aryl and heteroaryl and to the synthesis processes thereof. The invention also relates to pharmaceutical compositions comprising the compounds according to the invention, and to the uses thereof in medicine.

[ES] La presente invención se refiere a un compuesto de pARNi y un grupo R, donde R se selecciona entre alquilo, cicloalquilo, heterocicloalquilo, arilo y heteroarilo y sus procesos de síntesis. Además también se describen composiciones farmacéuticas que comprenden los compuestos de la invención, así como sus usos en medicina.

Consejo Superior de Investigaciones Científicas (España), CIBER-BBN, Aviño Andrés

A1 Solicitud de patente con informe sobre el estado de la técnica

Peer reviewed

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