Molécula de ADN con actividad aisladora de efectos de posición cromosomales en procesos de transferencia génica en células animales
Montoliu, Lluís; Giraldo, Patricia; Busturia, Ana;
Molécula de ADN con actividad aisladora de efectos de posición cromosomales en procesos de transferencia génica en células animales
La molécula de ADN comprende una secuencia de nucleótidos seleccionada entre (I) la secuencia de nucleótidos identificada como SEC. ID. N°: 1, o un fragmento de la misma; y (II) una secuencia de nucleótidos análoga a la secuencia definida en a), y tiene actividad aisladora de efectos de posición cromosomales en procesos de transferencia génica en células de animales. La molécula de ADN puede utilizarse para introducir transgenes y reducir la variabilidad de la expresión de transgenes en células de animales.
Referencia OEPM: P200101133.-- Fecha de solicitud: 18/05/2001.-- Titular: Consejo Superior de Investigaciones Científicas (CSIC).
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