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handle: 10261/4898
Polipéptido DREAM, nueva proteína reguladora de la expresión génica. Esta invención hace referencia a un factor de transcripción represor de la expresión de genes por su unión a las secuencias DRE, denominado DREAM (DRE Antagonist Modulator). DREAM es una nueva proteína humana que inhibe la expresión de genes regulados por secuencias DRE, entre ellos el gen prodinorfina, c-jun, c-fos e ICER. Esto abre nuevas perspectivas de control de la proliferación, diferenciación y/o muerte celular en procesos tumorales, degenerativos y autoinmunes.
Referencia OEPM: P9802667.-- Fecha de solicitud: 22/12/1998.-- Titular: Consejo Superior de Investigaciones Científicas (CSIC).
Peer reviewed
DRE Antagonist Modulator, Polipéptido DREAM, Expresión génica
DRE Antagonist Modulator, Polipéptido DREAM, Expresión génica
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