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Polipéptido DREAM, nueva proteína reguladora de la expresión génica

Authors: Naranjo, José Ramón; Mellström, Britt; Dompablo García, Isidro; Link, Wolfgang A.; Carrión Rodríguez, Ángel Manuel; Ledo Gómez, Francisco;

Polipéptido DREAM, nueva proteína reguladora de la expresión génica

Abstract

Polipéptido DREAM, nueva proteína reguladora de la expresión génica. Esta invención hace referencia a un factor de transcripción represor de la expresión de genes por su unión a las secuencias DRE, denominado DREAM (DRE Antagonist Modulator). DREAM es una nueva proteína humana que inhibe la expresión de genes regulados por secuencias DRE, entre ellos el gen prodinorfina, c-jun, c-fos e ICER. Esto abre nuevas perspectivas de control de la proliferación, diferenciación y/o muerte celular en procesos tumorales, degenerativos y autoinmunes.

Referencia OEPM: P9802667.-- Fecha de solicitud: 22/12/1998.-- Titular: Consejo Superior de Investigaciones Científicas (CSIC).

Peer reviewed

Keywords

DRE Antagonist Modulator, Polipéptido DREAM, Expresión génica

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selected citations
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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