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Doctoral thesis
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Doctoral thesis . 2010
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Doctoral thesis . 2012 . Peer-reviewed
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Recolector de Ciencia Abierta, RECOLECTA
Doctoral thesis . 2010 . Peer-reviewed
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https://doi.org/10.14201/gredo...
Doctoral thesis . 2019 . Peer-reviewed
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Thesis
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Doctoral thesis . 2010
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Thesis
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Sistemas de dos componentes y regulación de la producción de antibióticos en Streptomyces coelicolor

descriptionPublicationkeyboard_double_arrow_right Doctoral thesis , Thesis 24 Jul 2019 Spain Publisher:Ediciones Universidad de Salamanca
Authors: Yepes García, Ana;

doi: 10.14201/gredos.76583

handle: 10366/76583 , 10261/44882

Sistemas de dos componentes y regulación de la producción de antibióticos en Streptomyces coelicolor

Abstract

[ES]El presente trabajo pretende estudiar la relaci?n entre los sistemas de dos componentes AbrA1/A2 y AbrC1/C2/C3 y los procesos de producci?n de antibi?ticos y diferenciaci?n morfol?gica. La consecuci?n de este objetivo general se ha abordado en varias etapas: 1.- Estudio de la relevancia biol?gica de los TCSs AbrA1/A2 y AbrC1/C2/C3 en la producci?n de antibi?ticos y diferenciaci?n de S. coelicolor M145. 2.- An?lisis de las diferencias de expresi?n g?nica entre las cepas mutantes ?abrC1/C2/C3 y ?abrA1/A2 y la cepa silvestre S. coelicolor M145. 3.- Caracterizaci?n in vitro de los sistemas AbrA1/A2 y AbrC1/C2/C3 y b?squeda de sus dianas moleculares.

[EN]El presente trabajo pretende estudiar la relaci?n entre los sistemas de dos componentes AbrA1/A2 y AbrC1/C2/C3 y los procesos de producci?n de antibi?ticos y diferenciaci?n morfol?gica. La consecuci?n de este objetivo general se ha abordado en varias etapas: 1.- Estudio de la relevancia biol?gica de los TCSs AbrA1/A2 y AbrC1/C2/C3 en la producci?n de antibi?ticos y diferenciaci?n de S. coelicolor M145. 2.- An?lisis de las diferencias de expresi?n g?nica entre las cepas mutantes ?abrC1/C2/C3 y ?abrA1/A2 y la cepa silvestre S. coelicolor M145. 3.- Caracterizaci?n in vitro de los sistemas AbrA1/A2 y AbrC1/C2/C3 y b?squeda de sus dianas moleculares.

Country
Spain
Related Organizations
Keywords

2414.01 Antibióticos, Academic dissertations, Instituto de Microbiolog?a Bioqu?mica (IMB), Antibi?ticos, 2414.01 Antibi?ticos, Universidad de Salamanca (Espa?a), Universidad de Salamanca (España), Microbiología, Tesis y disertaciones académicas, Microbiology, Streptomyces, Tesis y disertaciones acad?micas, Antibiotics, Antibióticos, Microbiolog?a, Instituto de Microbiología Bioquímica (IMB)

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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