
handle: 10261/41619
[ES]: El envejecimiento es un proceso multifactorial que afecta a todos los órganos y sistemas del organismo. Aunque la reducción de la capacidad física asociada al envejecimiento es, hasta la fecha, inevitable, la práctica de hábitos de vida sanos y de la actividad física pueden reducir la incidencia de varias de las enfermedades asociadas al envejecimiento. En esta revisión recapitulamos los diferentes efectos del envejecimiento sobre el organismo y presentamos las nuevas evidencias que demuestran cómo el ejercicio es capaz de mejorar la fisiología celular en las personas mayores. Además, se indican los mediadores moleculares implicados en el efecto del ejercicio sobre la progresión del envejecimiento.
[EN]: Aging is a multifactorial process that affects all the organs and systems of the organism. Although the decline of physiological capacity associated with aging is, to date, unavoidable, practice of healthy life habits and physical activity can reduce the incidence of several aging-related diseases. In the present review we recapitulate the different effects of aging on the organism and show the new evidences that demonstrate how exercise is able to improve cell physiology in aged people. Moreover, the molecular mediators involved in the effect of exercise on aging progression are indicated.
This work was supported by DEP2005-00238-C04-04 and DEP2009-12019 grants of the Ministerio de Ciencia e Innovación and by the IMD2010SC0002 grant of the Consejería de Turismo, Comercio y Deporte de la Junta de Andalucía.
Peer reviewed
7 páginas.
Aging, Envejecimiento, Ejercicio, Mitocondria, Exercise, Mitochondria
Aging, Envejecimiento, Ejercicio, Mitocondria, Exercise, Mitochondria
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