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Formulations of cationic lipoamino acids with lower haemolytic power based on the formation of catanionic pairs

Authors: Pons Pons, Ramon; Pinazo Gassol, Aurora; Lozano Valdés, Neus; Rivas, Luis; Fernández-Reyes, María; Luque-Ortega, Juan Román; Pérez, Lourdes; +2 Authors

Formulations of cationic lipoamino acids with lower haemolytic power based on the formation of catanionic pairs

Abstract

[ES] La presente invención se refiere a una composición formada por un tensioactivo catiónico que es un diacilglicerol derivado de arginina y al menos un fosfolípidos. La estructura de esta composición confiere propiedades antibacterianas y antileishmanicas, con un menor poder hemolítico, por lo que son adecuadas para su uso para la fabricación de un medicamento para el tratamiento de infecciones causadas por bacterias y protozoos.

[EN] The present invention relates to a composition consisting of a cationic surfactant, which is a diacylglycerol derived from arginine, and at least one phospholipid. The structure of said composition imparts antibacterial and antileishmaniasis properties, with reduced haemolytic power, making said composition suitable for use in the production of a drug for treating infections caused by bacteria and protozoa.

A1 Solicitud de patente con informe sobre el estado de la técnica

Consejo Superior de Investigaciones Científicas (España)

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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