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Liposomes covered with the extracellular domain of the APO2L/TRAIL protein

Authors: Anel Bernal, Luis Alberto; Martínez Lorenzo, María José; Martínez-Lostao, Luis; Álava Martínez de Contrasta, María Angeles; Larrad Mur, Luis; Naval Irraberri, Javier; Basáñez, Gorka;

Liposomes covered with the extracellular domain of the APO2L/TRAIL protein

Abstract

[ES] La presente invención se encuadra dentro del campo de la biotecnología y la medicina. Específicamente, la presente invención se refiere a un compuesto que comprende un liposoma recubierto o decorado, al menos, con el dominio extracelular de la proteína AP02L1TRAIL y a su uso para la elaboración de un medicamento, preferiblemente, para el tratamiento de un cáncer o de enfermedades inflamatorias o autoinmunes, como la artritis reumatoide

[EN] The invention relates to the field of biotechnology and medicine. The invention specifically relates to a compound comprising a liposome covered or decorated at least with the extracellular domain of the AP02L1TRAIL protein, and to the use thereof for developing a medicament preferably for the treatment of a cancer or inflammatory or autoimmune diseases, such as rheumatoid arthritis.

Universidad de Zaragoza, Universidad del País Vasco, Consejo Superior de Investigaciones Científicas (España)

A2 Solicitud de patentes sin informe sobre el estado de la técnica

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
views
OpenAIRE UsageCountsViews provided by UsageCounts
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Cancer Research