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handle: 10261/41125
Retrotranscriptasa del VIH-1 de grupo O modificada. La presente invención se encuadra dentro del campo de la biotecnología. Más concretamente, se refiere a retrotranscriptasas aisladas de un virus de la inmunodeficiencia humana de tipo 1 (VIH-1) de grupo O y modificadas en la posición 75 y/o en la posición 478, que presentan una elevada fidelidad de copia y termoestabilidad, así como a su uso para llevar a cabo la retrotranscripción, amplificación o secuenciación de un ácido nucleico molde. La invención se refiere, además, a un método para obtener dichas retrotranscriptasas.
A1 Solicitud de patente con informe sobre el estado de la técnica
Consejo Superior de Investigaciones Científicas (España)
Peer reviewed
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