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handle: 10261/40890
[ES] Los filamentos intermedios son los elementos del citoesqueleto más resistentes; forman una red que rodea al núcleo y que se extiende hasta la periferia celular, interaccionando con la membrana plasmática. La familia de las citoqueratinas constituye el principal tipo de filamentos intermedios en la mayoría de células epiteliales. El objetivo de esta revisión es valorar la importancia de los filamentos intermedios en la estructura celular y su patrón de expresión en diferentes localizaciones. De este modo se podrá caracterizar la expresión y morfología de dichos filamentos en un estado fisiológico en contraposición con estados patológicos.
[EN] The intermediate filaments are the most resistant elements of the cytoskeleton; they develop a mesh that surrounds the nucleus and reach the cellular periphery, connecting to the plasmatic membrane. Cytokeratins are the main type of intermediate filaments in epithelial cells. The objective of our work is to assess the importance of intermediate filaments inside the cell structure and their expression pattern through different localizations. Thus the expression and morphology of these filaments will be characterized in a physiological condition in comparison with pathological process.
11 páginas, 1 figura, 2 tablas.
Peer reviewed
Protein, Mammary gland, Glándula mamaria, Filamentos intermedios, Citoqueratinas, Epithelium, Citoesqueleto, Vimentina, Epitelio, Proteína, Cytokeratins, Vimentin, Intermediate filaments, Cytoskeleton
Protein, Mammary gland, Glándula mamaria, Filamentos intermedios, Citoqueratinas, Epithelium, Citoesqueleto, Vimentina, Epitelio, Proteína, Cytokeratins, Vimentin, Intermediate filaments, Cytoskeleton
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