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Revisión sobre filamentos intermedios, con especial referencia a las citoqueratinas

Authors: Martínez Pérez, José Manuel; Martínez Rodríguez, J. M.;

Revisión sobre filamentos intermedios, con especial referencia a las citoqueratinas

Abstract

[ES] Los filamentos intermedios son los elementos del citoesqueleto más resistentes; forman una red que rodea al núcleo y que se extiende hasta la periferia celular, interaccionando con la membrana plasmática. La familia de las citoqueratinas constituye el principal tipo de filamentos intermedios en la mayoría de células epiteliales. El objetivo de esta revisión es valorar la importancia de los filamentos intermedios en la estructura celular y su patrón de expresión en diferentes localizaciones. De este modo se podrá caracterizar la expresión y morfología de dichos filamentos en un estado fisiológico en contraposición con estados patológicos.

[EN] The intermediate filaments are the most resistant elements of the cytoskeleton; they develop a mesh that surrounds the nucleus and reach the cellular periphery, connecting to the plasmatic membrane. Cytokeratins are the main type of intermediate filaments in epithelial cells. The objective of our work is to assess the importance of intermediate filaments inside the cell structure and their expression pattern through different localizations. Thus the expression and morphology of these filaments will be characterized in a physiological condition in comparison with pathological process.

11 páginas, 1 figura, 2 tablas.

Peer reviewed

Keywords

Protein, Mammary gland, Glándula mamaria, Filamentos intermedios, Citoqueratinas, Epithelium, Citoesqueleto, Vimentina, Epitelio, Proteína, Cytokeratins, Vimentin, Intermediate filaments, Cytoskeleton

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selected citations
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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