Effects of morphine on tumour growth.

descriptionPublicationkeyboard_double_arrow_right Article 10 Jan 2003 Spain English Publisher:Maghira & Maas PublicationsJournal:Neuro endocrinology letters, volume 23 (issn: 0172-780X,

Copyright policy )Funded by:NIH | OPIOID INVOLVEMENT IN NEU..., NIH | OLD WESTBURY NEUROSCIENCE...

Authors: Rasmussen, Mads; Zhu, Wei; Tonnesen, Jan; Cadet, P.; Tonnesen, Else; Stefano, G. B.;

pmid: 12080278

handle: 10261/377401

Effects of morphine on tumour growth.

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Abstract

Endogenous opiate alkaloids, such as morphine, and their peptide counterparts have been implicated in a wide variety of pharmacological and physiological functions. In addition to their use in the treatment of pain, opioids, appears to be important in the growth regulation of normal and neoplastic tissue. This review will focus on the infl uence of endogenous and exogenous opioids on tumour growth, with emphasis on immunoregulatory and antiproliferative mechanisms.

This work was supported by the following grants: NIDA 09010; NIMH 47392 and the NIH Fogarty INT 00045.

Peer reviewed

Country

Spain

Related Organizations

Spanish National Research Council
Spain
State University of New York at Potsdam
United States
Aarhus University Hospital
Denmark
COLLEGE AT OLD WESTBURY

Keywords

Endogenous opioid, Neoplasia, Morphine, Nitric oxide, Apoptosis, Analgesics, Opioid, Neoplasms, Humans, Cell Division, Cancer

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