Selective functionalization of the C−B bond in 1,2- bis(boronate) esters has emerged as a powerful tool to prepare 1,2- difunctionalized compounds with stereocontrol. Selective Suzuki crosscoupling, oxidation, amination, and homologation reactions serve as platforms to prepare a wide variety of compounds from a common intermediate. The exquisite selectivity offered and their easy preparation from feedstock material using a myriad of catalytic transformations make them attractive building blocks for the preparation of complex molecules. In this Perspective, we summarize the examples of selective C−B bond functionalization of vicinal bis(boronates), attending to the nature of the C−B bond functionalization

This work was supported by the MICINN (PID2019- 107380GB-I00)