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handle: 10261/34152
[ES] Un objeto de la presente invención lo constituye un procedimiento de fabricación y uso de arrays de proteínas y de otros tipos de arrays resistentes a la desnaturalización de sus componentes por deshidratación y/o temperatura, basado en el uso secuencial en dicho procedimiento de unos solventes concretos, la trehalosa y la trimetilamina N-óxido (TMAO), respectivamente. Igualmente, forma parte de la presente invención el array así fabricado y sus aplicaciones en el campo de la biología y biomedicina. El procedimiento puede emplearse en la protección de las características de los arrays de proteínas y otros tipos de arrays en condiciones ambientales sin necesidad de uso a corto plazo o de conservación en frío. Este punto disminuye sus costes de almacenaje y envío y permite la obtención de productos de mayor calidad.
[EN] The invention relates to a method for producing and using protein arrays and other types of arrays which are resistant to denaturalization of its components due to dehydration and/or temperature. The method is based in the sequential use of concrete solvents, trihalose and trimethylamine N-oxide (TMAO), respectively. The invention also relates to the array thus produced and its applications in the fields of biology and biomedicine. The method can be used to protect the characteristics of the protein arrays and other types of arrays under ambient conditions without requiring the use of short-term cold storage or cold preservation, which reduces storage and delivery costs and makes it possible to obtain better quality products.
Fecha de presentación internacional: 21.10.2004. - Titular: Consejo Superior de Investigaciones Científicas (CSIC)
Peer reviewed
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