Use of cyclopropenylsphingosine derivatives for the production of a ceramidase activity-modulating pharmaceutical composition, and applications thereof

Fabriàs, Gemma; Llebaria, Amadeu; Casas, Josefina; Triola Guillem, Gemma; Bedia, Carmen

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Recolector de Ciencia Abierta, RECOLECTA

Patent . 2005 . Peer-reviewed

Data sources: Recolector de Ciencia Abierta, RECOLECTA

Recolector de Ciencia Abierta, RECOLECTA

Other ORP type . 2011 . Peer-reviewed

Data sources: Recolector de Ciencia Abierta, RECOLECTA

Use of cyclopropenylsphingosine derivatives for the production of a ceramidase activity-modulating pharmaceutical composition, and applications thereof

descriptionPublicationkeyboard_double_arrow_right Patent , Other ORP type 01 Jan 2005

Authors: Fabriàs, Gemma; Llebaria, Amadeu; Casas, Josefina; Triola Guillem, Gemma; Bedia, Carmen;

handle: 10261/34134

Use of cyclopropenylsphingosine derivatives for the production of a ceramidase activity-modulating pharmaceutical composition, and applications thereof

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Abstract

[ES] La presente invención describe la actividad moduladora de los derivados de ciclopropenilesfingosina sobre las enzimas ceramidasas. Así es un objeto de la invención es el use de dichos compuestos en la elaboración de un composición farmacéutica útil para el tratamiento de distintas enfermedades (enf. de Faber, enfermedades cardiovasculares, inflamatorias y cáncer). Además, forma parte de la invención el use de dichas composiciones farmacéuticas en el tratamiento de las mencionadas enfermedades.

[EN] The invention relates to the modulating activity of cyclopropenylsphingosine derivatives on ceramidase enzymes. More specifically, the invention relates to the use of said compounds in the production of a pharmaceutical composition for the treatment of different diseases (Farber disease, cardiovascular diseases, inflammatory diseases and cancer). In addition, the invention relates to the use of said pharmaceutical compositions for the treatment of the aforementioned diseases.

Fecha de presentación internacional: 24.11.2004. - Titular: Consejo Superior de Investigaciones Científicas (CSIC)

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