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Identificación de genes asociados con la resistencia a Listonella anguillarum en el modelo animal pez cebra Danio rerio (Hamilton, 1822) mediante el análisis de perfiles de expresión diferencial

Authors: Rojo, I.; Castelruiz, Y.; Estonba, A.; Pardo, M.A. (Miguel Ángel);

Identificación de genes asociados con la resistencia a Listonella anguillarum en el modelo animal pez cebra Danio rerio (Hamilton, 1822) mediante el análisis de perfiles de expresión diferencial

Abstract

The zebrafish Danio rerio (Hamilton, 1822) - Listonella anguillarum infection model was used to identify genes associated with resistance to the infection. In the present study we analysed differential expression profiles in L. anguillarum infected zebrafish compared to control zebrafish, using DNA chip array (Affymetrix technology) and quantitative real-time PCR. The knowledge acquired in this study could be valuable in designing new strategies and tools for the selection of resistant individuals for the fish industry.

Se empleó el modelo de infección pez cebra Danio rerio (Hamilton, 1822) - Listonella anguillarum para identificar genes asociados con la resistencia a la infección. Se analizaron los perfiles de expresión diferencial en peces cebra infectados con la bacteria L. anguillarum y peces de control mediante chips de DNA y PCR cuantitativa a tiempo real. El conocimiento adquirido en este estudio será de gran valor a la hora de diseñar nuevas estrategias de selección de individuos resistentes en la industria piscícola.

Instituto Español de Oceanografía

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Spain
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Keywords

infección bacteriana, acuicultura, Medio Marino, expresión diferencial, Inmunidad innata, microarray

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selected citations
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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