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Autophagy
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Claim

Persulfidation is the mechanism underlying sulfide-signaling of autophagy

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 07 Jun 2021 Spain, Spain English Publisher:Informa UK LimitedJournal:Autophagy, volume 18, pages 695-697 (issn: 1554-8627, eissn: 1554-8635, Copyright policy )Funded by:EC | SSHelectPhagy
Authors: Gotor, Cecilia; Aroca, Angeles; Romero, Luis C.;

doi: 10.1080/15548627.2021.1936357

pmid: 34097571

pmc: PMC9037506

handle: 10261/304139 , 11441/112196

Persulfidation is the mechanism underlying sulfide-signaling of autophagy

Abstract

In this commentary, we highlight the findings described in a recent paper regarding the mechanism of H2S regulation of macroautophagy/autophagy in mammalian cells and discuss the similarities/divergencies with plant cells. The main outcome is that the posttranslational modification of thiol groups of cysteine residues to form persulfides is a conserved molecular mechanism.

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Spain, Spain
Related Organizations
Keywords

Mammals, Hydrogen sulfide, GAPDH, Arabidopsis, Persulfidated cysteine, Sulfides, Stress, Autophagy, Animals, Posttranslational modification, Cysteine, Hydrogen Sulfide, Commentary and Views, Protein Processing, Post-Translational, Signal Transduction

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
views
OpenAIRE UsageCountsViews provided by UsageCounts
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15
Top 10%
Average
Top 10%
457
105
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