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Eficacia de N-desmetiltamoxifeno solo y en combinación con colistimetato sódico y tigeciclina, en la neumonía experimental por Escherichia coli y Acinetobacter baumannii

Authors: Vila-Domínguez, Andrea; Herrero Espejo, S.; Cerrillo Matilla, J.; Rodríguez López, J.; Smani, Younes; Pachón, Jerónimo; Jiménez Mejías, M. E.; +1 Authors

Eficacia de N-desmetiltamoxifeno solo y en combinación con colistimetato sódico y tigeciclina, en la neumonía experimental por Escherichia coli y Acinetobacter baumannii

Abstract

Introducción/Objetivos: El reposicionamiento de fármacos, es una alternativa en el desarrollo de nuevos fármacos frente a infecciones por bacilos gramnegativos multirresistentes. El objetivo fue evaluar in vivo la eficacia de Ndesmetiltamoxifeno (N-DTAM), en monoterapia y en combinación con antimicrobianos, en un modelo murino de neumonía experimental por cepas de Escherichia coli y Acinetobacter baumannii.

Trabajo presentado en el 1er Congreso de la Sociedad Andaluza de Microbiología Clínica y Enfermedades Infecciosas, celebrado en Málaga (España) del 16 al 18 de noviembre de 2022.

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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