
handle: 10261/288693
[ES] En esta charla, revisaré diferentes aplicaciones en biomedicina que hemos desarrollado utilizando películas metálicas nanocolumnares (NCFs). Esas películas se fabrican mediante un método físico: deposición en ángulo oblicuo mediante pulverización catódica con magnetrón. Esta técnica es respetuosa con el medio ambiente, ya que se realiza a temperatura ambiente en un solo paso y no implica productos químicos (por tanto, sin problemas de reciclado). Además, esta estrategia se puede escalar a grandes superficies, lo que representa un enfoque válido para la producción industrial de películas nanoestructuradas [1]. Después de una breve introducción sobre el método de fabricación, mostraré varias aplicaciones de estos sistemas en biomedicina. En particular, las NCFs de Ti se pueden usar como recubrimientos antibacterianos para implantes ortopédicos [1,2,3], las NCFs de Pt presentan interesantes propiedades para su uso como bioelectrodos en una plataforma de estimulación eléctrica in vitro [5] y las NCFs de Au son excelentes soportes para la identificación de biomoléculas en espectroscopia Raman mejorada en superficie, SERS [5,6].
[EN] In this talk, I will review different applications in biomedicine that we have developed using metallic nanocolumnar films (NCFs). Those films are fabricated by a physical method: glancing angle deposition using magnetron sputtering. This technique is environmentally friendly, since it is carried out at RT in a single step and does not involve chemical products (therefore, without recycling problems). Moreover, this strategy can be scaled up to large surfaces, representing a valid approach for the industrial production of nanostructured films [1]. After a brief introduction about the fabrication method, I will show several applications of these systems in biomedicine. In particular, Ti NCFs can be used as antibacterial coatings for orthopedic implants [1,2,3], Pt NCFs show improved properties as bioelectrodes for an electric stimulation platform in vitro [5], and Au NCFs are excellent substrates for the identification of biomolecules in Surface Enhanced Raman Spectroscopy, SERS [5,6].
Resumen del trabajo presentado en el 1st Innovative Technologies for Medical Applications, celebrado en Bucaramanga (Colombia), los días 1 y 2 de diciembre de 2022
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