The synthesis of enantiomerically pure (2R)-α-methylisoserine

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1996 English Publisher:Elsevier BVJournal:Tetrahedron, volume 52, pages 687-694 (issn: 0040-4020,

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Authors: Cativiela, Carlos; Díaz de Villegas, María D.; Gálvez, José A.;

doi: 10.1016/0040-4020(95)00919-1

handle: 10261/272905

The synthesis of enantiomerically pure (2R)-α-methylisoserine

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Abstract

The title compound was prepared by diastereoselective methylation of chiral (1S,2R,4R)-10-dicyclohexylsulfamoylisobornyl acetoxycyanoacetate and subsequent nitrile hydrogenation. This work was supported by the Dirección General de Investigación Científica y Técnica, project number PB94-0578, Peer reviewed

Related Organizations

Spanish National Research Council
Spain
University of Zaragoza
Spain

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