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Claim

Electrochemiluminescent nanostructured DNA biosensor for SARS-CoV-2 detection

descriptionPublicationkeyboard_double_arrow_right Article 01 Apr 2022 Spain English Publisher:Elsevier BVJournal:Talanta, volume 240, page 123,203 (issn: 0039-9140, Copyright policy )
Authors: Laura Gutiérrez-Gálvez; Rafael del Caño; Iris Menéndez-Luque; Daniel García-Nieto; Micaela Rodríguez-Peña; Mónica Luna; Teresa Pineda; +3 Authors

doi: 10.1016/j.talanta.2021.123203

pmid: 34998140

pmc: PMC8719920

handle: 10261/268602 , 10486/719474 , 10396/27084 , 20.500.12614/2773

Electrochemiluminescent nanostructured DNA biosensor for SARS-CoV-2 detection

Abstract

This work focuses on the development of an electrochemiluminescent nanostructured DNA biosensor for SARS-CoV-2 detection. Gold nanomaterials (AuNMs), specifically, a mixture of gold nanotriangles (AuNTs) and gold nanoparticles (AuNPs), are used to modified disposable electrodes that serve as an improved nanostructured electrochemiluminescent platform for DNA detection. Carbon nanodots (CDs), prepared by green chemistry, are used as coreactants agents in the [Ru(bpy)3]2+ anodic electrochemiluminescence (ECL) and the hybridization is detected by changes in the ECL signal of [Ru(bpy)3]2+/CDs in combination with AuNMs nanostructures. The biosensor is shown to detect a DNA sequence corresponding to SARS-CoV-2 with a detection limit of 514 aM.

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Spain
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Keywords

SARS-CoV-2, COVID-19, Metal Nanoparticles, Química, Biosensing Techniques, DNA, Electrochemical Techniques, 540, Article, AuNMs, Nanostructures, Luminescent Measurements, Humans, Gold, DNA biosensor

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selected citations
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
views
OpenAIRE UsageCountsViews provided by UsageCounts
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