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Non-human animal model which can be used to identify pharmaceutical compounds which regulate the hedgehog pathway, and applications thereof

Authors: Guerrero Vega, Isabel; Callejo de Prado, Ainhoa Itziar; Culi, Joaquim;

Non-human animal model which can be used to identify pharmaceutical compounds which regulate the hedgehog pathway, and applications thereof

Abstract

La presente invención describe un modelo animal no humano que el bote sea utilizado identificar los compuestos farmacéuticos que regulan la formación, la difusión y la recepción de partículas lipoproteic usando el hedgehog. Estos compuestos farmacéuticos que regulan la formación, la difusión y la recepción de partículas lipoproteic usando el bote del hedgehog sean utilizados hacer un medicamento para tratar las enfermedades humanas, preferiblemente cáncer.

The present invention describes a non-human animal model which can be used to identify pharmaceutical compounds which regulate the formation, diffusion and reception of lipoproteic particles using hedgehog. These pharmaceutical compounds which regulate the formation, diffusion and reception of lipoproteic particles using hedgehog can be used to make a medicament for treating human diseases, preferably cancer.

Fecha de solicitud: 03/04/2008.- Titular: Consejo Superior de Investigaciones Científicas (CSIC)

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
views
OpenAIRE UsageCountsViews provided by UsageCounts
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Cancer Research