This workshop is dedicated to technological advances that allow precise control of gene expression and protein abundance. Ground breaking work by Andrew Fire and Craig C. Mello on RNAi as a potent tool to silence gene expression has had a tremendous impact on the C. elegans field and beyond. Nevertheless, additional layers of manipulation are important to obtain experimental alternatives that often provide faster, more precise and/or reversible regulation of gene activity. Leading researchers involved in the development of tools for drug inducible gene expression, genome recombination and targeted protein degradation and localization will share their recent advances and experience with the audience through open discussion.

Trabajo presentado en la 23rd International C. elegans Conference, celebrada en modalidad virtual el 21 de junio de 2021.