Selenium (Se) is an essential micronutrient as it is an integral component of antioxidant enzymes. Moreover organo Se species exert a chemopreventive action against cancer through inhibition of proinflammatory responses. Se intake, especially in Eastern European countries, is below the recommended dietary allowances (55 ug/day formen and women). Sauerkraut is a source of health promoting compounds such as antioxidants and glucosinolate (GLS) hydrolysis products and results from the lactic acid fermentation of white cabbage. Lactic acid bacteria are able to transform inorganic Se into organoSe compound during fermentation process. Therefore, lactic acid fermentation of white cabbage with selenium could be used as an approach to increase human Se intake and health promoting properties of sauerkraut. The objective of this study was to obtain Se-enriched sauerkraut from white cabbage (Brassica oleracea L. var. capitata cv. Megaton). In addition, the potential antioxidant and anti-inflammatory activity of selenized sauerkrauts as well as sorne of its bioactive compounds was also investigated. For this purpose 0.3 mg of sodium selenite/Kg of fresh cabbage (1.6 mg Se per Kg of dried cabbage) was acldecl. Cabbage was further submmitted to natural fermentation at 0.5% NaCl for 7 days. Selenium species, indole GLS hydrolysis products [ascorbigen (ABG). indol-3-carbinol (I3C) and indol-3-acetonitrile and (I3A) and vitamin C (vitC) were analysed by ICP-LC, LC and CE, respectively. Antioxidant capacity was determined 111 sauerkraut extracts as oxygen radical antioxidant capacity (ORAC). Sauerkraut extracts, Se-methylselenocysteine (MeSeCys) and ABG were tested by their ability to inhibit nitrie oxide (NO) production in LPS-inclucecl RAW264.7 macrophages. Results showed that total Se concentration from 0.07 to 1.29 ug/g dry matter: Indole GLS hydrolisis product increase noticeably after fermentation.

Resumen del póster presentado al EuroFoodChem XVI, celebrado en Gdansk (Polonia) del 6 al 8 de julio de 2011.

This research was supported by projects AGL2007- 63462, CTQ-2008- 05925) and S2009/AGR-1464 (ANALISYC-II).

Peer reviewed