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Recolector de Ciencia Abierta, RECOLECTA
Patent . 2018 . Peer-reviewed
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Recolector de Ciencia Abierta, RECOLECTA
Other ORP type . 2021 . Peer-reviewed
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Recolector de Ciencia Abierta, RECOLECTA
Patent . 2018 . Peer-reviewed
Data sources: Recolector de Ciencia Abierta, RECOLECTA
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Recolector de Ciencia Abierta, RECOLECTA
Other ORP type . 2021 . Peer-reviewed
Data sources: Recolector de Ciencia Abierta, RECOLECTA
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Uso de efavirenz para el tratamiento de enfermedades de almacenamiento lipídico

descriptionPublicationkeyboard_double_arrow_right Patent , Other ORP type 01 Jan 2018
Authors: Ledesma, M. Dolores; Mitroi, Daniel;

handle: 10261/244577 , 10261/244582

Uso de efavirenz para el tratamiento de enfermedades de almacenamiento lipídico

Abstract

La presente invención se refiere al uso de efavirenz para fabricar un medicamento para el tratamiento de enfermedades de almacenamiento lipídico tales como enfermedades de Niemann-Pick . Mediante la activación de CYP46, que estimula la eliminación de colesterol en las neuronas , entre otros lípidos ,efavirenz es capaz de normalizar los niveles de estos lípidos y la función neuronal. Efavirenz también se puede usar en combinación con otro principio activo considerado eficaz para el tratamiento de estas enfermedades, para mejorar los efectos terapéuticos

A1 Solicitud de patente con informe sobre el estado de la técnica

Consejo Superior de Investigaciones Científicas (España)

Peer reviewed

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download
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
views
OpenAIRE UsageCountsViews provided by UsageCounts
downloads
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0
Average
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58
93
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