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DIGITAL.CSIC
Article . 2021 . Peer-reviewed
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Influencia del nivel proteínico dietario sobre el patrón electroforético y los niveles de Ig G e Ig M plasmáticos en ratas gestantes y sus neonatos

Authors: Varela, Pilar; Muñoz Martínez, Emilia; Marcos, Ascensión; Unzaga, María Teresa;

Influencia del nivel proteínico dietario sobre el patrón electroforético y los niveles de Ig G e Ig M plasmáticos en ratas gestantes y sus neonatos

Abstract

[ES]: En vista de la influencia que los estados nutricional y fisiológico tienen sobre la capacidad inmunológica del individuo, se llevó a cabo un estudio de las modificaciones que inducen tres niveles de proteína en la dieta: 4%, 10% (control) y 20% sobre la tasa de inmunoglobulinas G y M plasmáticas, así como los niveles de proteínas totales en plasma (PPT) y sus fracciones, en ratas no gestantes (NG) y gestantes (G) y sus neonatos. Efecto de la dieta en ratas adultas - En ratas no gestante aparece un incremento en la tasa de Ig G por acción de la dieta alta en proteína. Los niveles de PPT disminuyen con las dietas alta y baja en proteína. En animales G disminuyen ambas Ig con las dos dietas experimentales (4% y 20%), mientras la tasa de PPT se incrementa a medida que aumenta la cantidad de proteína ingerida. Efecto de la gestación - Los niveles de Ig G e Ig M se elevan con las dietas del 4% y 10%. Sin embargo, estos niveles sufren un descenso cuando las ratas ingieren la dieta del 20% de proteína. La tasa de PPT desciende con el déficit proteínico dietario y aumenta con la dieta más alta en proteína. Efecto de la dieta en neonatos - Los niveles de Ig M sólo se detectaron en la progenie de ratas alimentadas con las dietas alta y baja en proteína. Por su parte, la tasa de PPT se incrementa en función directa de la ingesta proteínica dietaria

[EN]: In view of the influence that nutritional and physiological status exert on the immunological capacity of the subject, a study was carried out for the purpose of studying the changes induced by three protein levels in the diet: (4°/o, 10° jo (control), and 20°/o) on total plasma proteins (TPP) and their fractions, as well as Ig G and Ig M levels in non-pregnant (NP) and pregnant (P) rats and their offspring. Effect of the diet on adult rats — In non-pregnant rats submitted to the high protein diet, Ig G levels increased while TPP decreased in P rats fed on 4°/o and 20°/o protein diets. The higher the protein level in the diet, the higher were the TPP values. Effect of pregnancy — Ig G and Ig M levels suffered an increase in rats fed the 4°/o and 10°/o protein diets, while a decrease was observed in rats submitted to the 20°/'o protein level diet. The TPP rate diminished in rats fed on the low protein diets, and increased when the highest protein diet was administered. Effect of the diet on offspring — Ig M levels were only detected in neonates from rats fed with the low and high protein diets. Moreover, the TPP rate increased as a direct function o f the dietary protein intake.

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selected citations
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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