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Recolector de Ciencia Abierta, RECOLECTA
Conference object . 2021
Full-Text: http://dx.doi.org/10.3324/haematol.2020.s3
Data sources: Recolector de Ciencia Abierta, RECOLECTA
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Recolector de Ciencia Abierta, RECOLECTA
Conference object . 2020
Data sources: Recolector de Ciencia Abierta, RECOLECTA
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Claim

Utilidad clínica del biomarcador bismetilgliotoxina para el manejo de pacientes en riesgo de infección viral después del trasplante de progenitores hematopoyético alogénico

descriptionPublicationkeyboard_double_arrow_right Conference object 01 Jan 2020 Spanish Publisher:Ferrata Storti Foundation (Haematologica)
Authors: Vallejo, Miren; Viguria, M. Cruz; Zudaire Ripa, Teresa; Solán, Laura; Gayoso, J.; Champ, Diana; Domingo, María Pilar; +10 Authors

handle: 10261/232462

Utilidad clínica del biomarcador bismetilgliotoxina para el manejo de pacientes en riesgo de infección viral después del trasplante de progenitores hematopoyético alogénico

Abstract

Gliotoxina (GT) es la toxina producida mayoritariamentepor las cepas de Aspergillus fumigatus(AF). Bismetil-gliotoxina (bmGT),metabolito secundario y de mayor estabilidad que GT, se ha detectadoen el suero de pacientes con infección fúngica invasiva (IFI) y constituyeun marcador más sensible y específico que el galactomanano (GM) enel diagnóstico de IFI. Estudios in vitro han demostrado que entre las fun-ciones inmunosupresoras de la GT está la de bloquear la función fisi-ológica de los linfocitos T (LT). El objetivo del estudio es identificar lapresencia de bmGT en pacientes que reciben un trasplante de progen-itores hematopoyéticos alogénico (alo-TPH) y conocer su potencial in-munoregulador sobre la funcionalidad de los LT anti-virales de estospacientes.

2 tablas.-- PO-195.-- Póster presentado en el LXII Congreso Nacional de la SEHH XXXVI Congreso Nacional de la SETH, Virtual, 26-30 de octubre, 2020.

Keywords

Biomarcadores, Bismetilgliotoxina, Trasplante de progenitores hematopoyéticos

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selected citations
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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