Pharmacological activity of the fraction isolated from virgin olive oil containing the sterols and triterpenic alcohols

descriptionPublicationkeyboard_double_arrow_right Article 30 Apr 1997Publisher:Editorial CSICJournal:Grasas y Aceites, volume 48, pages 93-95 (issn: 0017-3495, eissn: 1988-4214,

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Authors: R. de la Puerta; R. Maestro Durán; V. Ruiz Gutiérrez;

doi: 10.3989/gya.1997.v48.i2.775

handle: 10261/21856

Pharmacological activity of the fraction isolated from virgin olive oil containing the sterols and triterpenic alcohols

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Abstract

The fraction of sterols and triterpenic dialcohols from unsaponifiable of virgin olive oil has been tested for Its possible antiinflamatory activity. The topical administration of these products produced a potent antioedematous effect, in the auricular oedema induced by TPA (12-0-tetradecanoylphorbol acetate) in experimental animals. This test has been widely used to determine the antiinflamatory action of phospholipase A2 inhibitors. The measure of myeloperoxidase, marker enzyme of the accumulation of neutrophils in the inflamed tissue, demonstrated a significant reduction of the cellular infiltration produced by assayed fraction.

Related Organizations

Spanish National Research Council
Spain
Instituto de la Grasa
Spain

Keywords

Esterol., Nutrition. Foods and food supply, Aceite de oliva virgen, antiinflamatory activity, virgin olive oil., Esterol, Alcohol triterpénico, triterpene alcohol, sterol, Triterpene alcohol, Virgin olive oil, TX341-641, Antiinflamatory activity, Virgin olive oil., Actividad antiinflamatoria, Sterol

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