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Cell Progeny in the Olfactory Bulb after Targeting Specific Progenitors with Different UbC-StarTrack Approaches

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 13 Mar 2020 Spain English Publisher:MDPI AGJournal:Genes, volume 11, page 305 (eissn: 2073-4425, Copyright policy )
Authors: Rebeca Sánchez-González; María Figueres-Oñate; Ana Cristina Ojalvo-Sanz; Laura López-Mascaraque;

doi: 10.3390/genes11030305

pmid: 32183100

pmc: PMC7140809

handle: 10261/205593

Cell Progeny in the Olfactory Bulb after Targeting Specific Progenitors with Different UbC-StarTrack Approaches

Abstract

The large phenotypic variation in the olfactory bulb may be related to heterogeneity in the progenitor cells. Accordingly, the progeny of subventricular zone (SVZ) progenitor cells that are destined for the olfactory bulb is of particular interest, specifically as there are many facets of these progenitors and their molecular profiles remain unknown. Using modified StarTrack genetic tracing strategies, specific SVZ progenitor cells were targeted in E12 mice embryos, and the cell fate of these neural progenitors was determined in the adult olfactory bulb. This study defined the distribution and the phenotypic diversity of olfactory bulb interneurons from specific SVZ-progenitor cells, focusing on their spatial pallial origin, heterogeneity, and genetic profile.

Country
Spain
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Keywords

Development, Article, Mice, Cell Movement, Interneurons, StarTrack, Lateral Ventricles, Animals, Cell Lineage, neural progenitor cell, Neural progenitor cells, development, Olfactory interneuron, cell fate, Stem Cells, Cell Differentiation, in utero electroporation, Olfactory Bulb, Cell fate, Olfactory interneurons, Neural progenitor cell, heterogeneity, Heterogeneity, In utero electroporation

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
views
OpenAIRE UsageCountsViews provided by UsageCounts
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OpenAIRE UsageCountsDownloads provided by UsageCounts
9
Top 10%
Average
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37
119
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