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handle: 10045/68047 , 10261/190567
This review summarizes the trends in the formation of complex or not so complex heterocyclic structures through 1,3-dipolar cycloadditions of azomethine ylides. Diastereo- and enantioselective processes as well as non-asymmetric cycloadditions constitute very important synthetic tools for achieving these compounds. This review covers the literature from 2015 through 2016 and organizes the research in terms of biologically important heterocycles and natural products from cascade 1,3-dipolar cycloadditions of azomethine ylides to the simpler forms of 1,3-dipolar cycloaddition.1 Introduction2 Synthesis of Spirooxindoles3 Synthesis of Spiropyrrolidines4 Synthesis of Spiropiperidines and Piperidines5 Synthesis of Pyrrolidines and Fused Pyrrolidines6 Synthesis of Pyrrolizidines and Indolizidines7 Synthesis of Quinolone and Isoquinolines8 Conclusions
Natural products, Química Orgánica, Heterocycles, Dipolar cycloaddition, Bioactivity, Azomethine ylide
Natural products, Química Orgánica, Heterocycles, Dipolar cycloaddition, Bioactivity, Azomethine ylide
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