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Synthesis
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Synthesis
Article . 2017 . Peer-reviewed
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Current Trends towards the Synthesis of Bioactive Heterocycles and Natural Products Using 1,3-Dipolar Cycloadditions (1,3-DC) with Azomethine Ylides

Authors: Dondas, H. Ali; Retamosa, Maria de Gracia; Sansano, Jose M.;

Current Trends towards the Synthesis of Bioactive Heterocycles and Natural Products Using 1,3-Dipolar Cycloadditions (1,3-DC) with Azomethine Ylides

Abstract

This review summarizes the trends in the formation of complex or not so complex heterocyclic structures through 1,3-dipolar cy­cloadditions of azomethine ylides. Diastereo- and enantioselective processes as well as non-asymmetric cycloadditions constitute very important synthetic tools for achieving these compounds. This review covers the literature from 2015 through 2016 and organizes the research in terms of biologically important heterocycles and natural products from cascade 1,3-dipolar cycloadditions of azomethine ylides to the simpler forms of 1,3-dipolar cycloaddition.1 Introduction2 Synthesis of Spirooxindoles3 Synthesis of Spiropyrrolidines4 Synthesis of Spiropiperidines and Piperidines5 Synthesis of Pyrrolidines and Fused Pyrrolidines6 Synthesis of Pyrrolizidines and Indolizidines7 Synthesis of Quinolone and Isoquinolines8 Conclusions

Country
Spain
Keywords

Natural products, Química Orgánica, Heterocycles, Dipolar cycloaddition, Bioactivity, Azomethine ylide

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
views
OpenAIRE UsageCountsViews provided by UsageCounts
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142
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