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Estudio de la actividad antimicrobiana de compuestos orgánicos

Authors: Garrido-Orduña, Cristina; Pérez de la Lastra, José Manuel; González Martín, Concepción C.; Boto, Alicia;

Estudio de la actividad antimicrobiana de compuestos orgánicos

Abstract

La resistencia a antimicrobianos es una de las mayores amenazas para la salud pública en todo el mundo; por ello el desarrollo de nuevos compuestos antimicrobianos está cobrando gran interés. En este trabajo se realiza el cribado biológico de quimiotecas de compuestos nitrogenados frente a bacterias Gram+ y Gram-, potencialmente patógenas. Muchos de estos compuestos son péptidos antimicrobianos (AMPs), los cuales se definen como péptidos pequeños (de 30-40 aminoácidos), con carga neta positiva, alto contenido de aminoácidos hidrofóbicos y actividad antimicrobiana no específica, por lo que la aparición de resistencias es muy baja.

Este trabajo se financió con el Proyecto SAF-2013-48399-R, Plan Estatal de I+D, Ministerio de Economía y Competitividad (MINECO). CG agradece al Sistema Nacional de Garantía Juvenil y al Fondo Social Europeo su contrato.

Trabajo presentado en la XXI Semana Científica “Antonio González”, celebrada en San Cristóbal de La Laguna, Tenerife (España) del 24 al 27 de octubre de 2017.

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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