Propargyl vinyl ethers and the propargyl Claisen rearrangement: synthesis of allenes and beyond
Propargyl vinyl ethers and the propargyl Claisen rearrangement: synthesis of allenes and beyond
Propargyl vinyl ethers (PVEs) constitute a privileged group of small size, structurally simple, readily available, and densely functionalized scaffolds. The key to the chemical reactivity encoded in these structures is the [3,3]-propargylic sigmatropic rearrangement which initially affords functionalized allenes (see scheme). Our group has been working on the synthetic potential of these platforms in accessing a large number of different compounds using thermal activation in a laboratory microwave apparatus. In this communication the synthesis of salicylaldehyde derivatives and 1,2-dihydropyridines will be highlighted.
This research was supported by the Spanish and European MICINN RDF (CTQ2008-06806-C02-02 and CTQ2011-28417-C02-02). L. C. thanks the Spanish MEC for a FPI grant.
Trabajo presentado en la XXV Reunión Bienal de Química Orgánica celebrada en Alicante del 4 al 6 de junio de 2014.
Peer Reviewed
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).0 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Average
Citations provided by BIP!Popularity provided by BIP!