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handle: 10261/179888 , 10261/179890 , 10261/179882
[ES] La presente invención se refiere a linfocitos, preferiblemente que han sido transinfectados desde células dendríticas con una bacteria, preferiblemente linfocitos T CD4+, preferiblemente Listeria monocytogenes, donde dicha bacteria comprende un péptido tumoral. También se refiere al uso de los linfocitos para terapia y/o tratamiento de tumores sólidos, preferiblemente melanoma, al kit o dispositivo que los comprende para dicho fin. Además, también se refiereal método de transinfección de los mismos.
[EN] The present invention relates to lymphocytes, preferably that have been transinfected from dendritic cells with a bacterium, preferably CD4+ T cells, preferably Listeria monocytogenes, wherein said bacterium comprises a tumor peptide. It also relates to the use of lymphocytes for therapy and/or treatment of solid tumors, preferably melanoma, the kit or device that comprises same for this purpose. Furthermore, it also refers to the transinfection method thereof.
Consejo Superior de Investigaciones Científicas (España), Universidad Autónoma de Madrid, Fundación para la Investigación Biomédica del Hospital de la Princesa
E Solicitud de patente europea
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