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Liposome-encapsulated bicelles and use thereof in diluted systems

Authors: Maza, Alfons de la; Barbosa-Barros, Lucyana; López Serrano, Olga; Cocera Núñez, Mercedes; Rodríguez Delgado, Gelen; Rubio, Laia; Planas, Anna M.; +1 Authors

Liposome-encapsulated bicelles and use thereof in diluted systems

Abstract

[ES] La presente invención tiene como finalidad preservar la morfología de las bicelas en ambientes con alto contenido en agua, por ello, la invención se refiere a un liposoma que comprende, en su solución acuosa interna, al menos, una bicela. La concentración de bicelas en dicha solución es de entre el 5 y 25% en peso seco con respecto al liposoma final. La invención también se refiere al uso de dichos liposomas para el encapsulado de principios activos, así como a su uso como medicamento o para la elaboración de un producto cosmético. Además, la presente invención se refiere al método de obtención de dichos liposomas.

[EN] The aim of the invention is to preserve the morphology of bicelles in high-water-content environments. For this purpose, the invention relates to a liposome comprising, in its internal aqueous medium, at least one bicelle. The bicelles concentration in said aqueous means is between 5 and 25 % dry weight in relation to the end liposome. The invention also relates to the use of said liposomes for the encapsulation of active principles, as well as to the use thereof as a medicament or to produce a cosmetic product. The invention further relates to the method for obtaining said liposomes.

Consejo Superior de Investigaciones Científicas (España)

B2 Patente con examen previo

Peer reviewed

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selected citations
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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