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handle: 10261/175150
[ES] Procedimiento general de obtención de biocatalizadores que comprende la inmovilización de enzimas durante la síntesis de materiales metalo-orgánicos. La presente invención propone un procedimiento general de obtención de biocatalizadores que comprende la inmovilización in-situ de enzimas, en la mesoporosidad intercristalina formada por la agregación de nanocristales durante la síntesis de un material metalo-orgánico (MOF). El procedimiento de la invención permite alcanzar un alto contenido de enzima sobre el soporte, minimizar la reducción de la eficiencia catalítica en relación con la de la misma enzima libre y reducir las pérdidas por lixiviado, solventando de esta forma las limitaciones identificadas en los métodos de obtención de biocatalizadores conocidos basados en la inmovilización de enzimas in-situ. La invención también se refiere a los biocatalizadores directamente obtenidos por el procedimiento.
[EN] The present invention relates to a general method for obtaining biocatalysts which comprises immobilising enzymes in situ in the intercrystalline mesoporosity formed by nanocrystal aggregation during the synthesis of a metallo-organic material (MOF). The method of the invention allows the obtainment of a high enzyme content on the support , the minimisation of the reduction of catalytic efficiency in relation to that of the free enzyme, and the reduction of losses as a result of leaching, thereby resolving the limitations identified in the known methods for obtaining biocatalysts, which are based on in-situ enzyme immobilisation. The invention also relates to the biocatalysts directly obtained by the method.
Consejo Superior de Investigaciones Científicas (España)
A1 Solicitud de adición a la patente
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