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handle: 10261/175098
[ES] Se han identificado los genes Tert y Brdt de la lubina y se ha analizado su expresión en diferentes órganos y tejidos. La expresión del gen Tert presentó una distribución ubicua, en consonancia con el continuo crecimiento de los peces y con su gran capacidad para la regeneración. Sin embargo, la expresión del gen Brdt era significativamente más elevada en ovario y testículo, con niveles bajos en cerebro, lo que sugiere que en la lubina la expresión del gen Brdt juega un papel importante en la gametogénesis, pero también podría participar en otros procesos que no son bien conocidos. En mamíferos, se ha descrito que la subunidad enzimática de la telomerasa (Tert) es un componente de los telómeros de las células germinales, que se mantiene durante toda la espermatogénesis como un componente estructural sin afectar el alargamiento de los telómeros. Por otro lado, la proteína BRDT es esencial para el progreso normal de la espermatogénesis.
[EN] We have identified the seabass Tert and Brdt genes and analyzed their expression in different organs systems and tissues. Tert gene expression showed ubiquitous distribution, in agreement with continuous fish growth and high capability for regeneration. Nevertheless, Brdt gene expression was significantly higher in testis and ovary, with lower levels in brain. These results suggest that in seabass, the Brdt gene expression can play an important role in gametogenesis, but it could also be implicated in other processes that are not as well known. In mammalian, the telomerase enzymatic subunit (Tert) is a component of telomeres of germ cells, which is maintained throughout spermatogenesis as a structural component without affecting telomere elongation. On the other hand, bromodomain testis-specific (BRDT) protein is essential for the normal process of spermatogenesis.
Trabajo presentado en el XV Congreso Nacional de Acuicultura y el I Congreso Ibérico de Acuicultura, celebrados en Huelva del 13 al 16 de octubre de 2015.
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