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Método de obtención de un array de micropartículas planares con multiplexado molecular superficial, array obtenido y su uso

Authors: Esteve i Tintó, Jaume; Plaza, José Antonio; Duch Llobera, Marta; Torras Andrés, Núria; Pérez García, María Luisa; Agusil, Juan Pablo;

Método de obtención de un array de micropartículas planares con multiplexado molecular superficial, array obtenido y su uso

Abstract

[ES] Método de obtención de un array de micropartículas planares con multiplexado molecular superficial, array obtenido y su uso. La invención se refiere a la fabricación controlada de un array de micropartículas planares con multiplexado de moléculas en su superficie, cuya misión es funcionar como sensores y/o actuadores moleculares. La presente invención propone una matriz (array) de micropartículas en cuya superficie están impresos todos los componentes moleculares necesarios para dotarlas de funcionalidad. Es posible fabricar este producto gracias al diseño de un proceso en el cual los diferentes elementos moleculares son multiplexados en la superficie de cada partícula mientras están soportadas sobre un sustrato gracias al grabado de un pie debajo de ellas. Estas micropartículas pueden ser liberadas mecánicamente del soporte donde se fabrican por un método mecánico de ruptura controlada, que es un método no agresivo químicamente y por tanto no afecta a las moléculas previamente impresas en su superficie. El array y las partículas que contiene presentan una gran versatilidad en aplicaciones tanto químicas y/o biológicas.

[EN] The invention relates to the controlled production of an array of planar microparticles with the multiplexing of molecules on the surface thereof, intended to function as molecular sensors and/or actuators. The invention relates to a matrix (array) of microparticles, the surface thereof being printed with all of the molecular components required to provide same with functionality. This product can be produced thanks to the design of a process in which different molecular elements are multiplexed on the surface of each particle while they are supported on a substrate by means of a structural foot engraved below same. These microparticles can be released mechanically from the support where they are produced, by means of a controlled mechanical rupture method which is not chemically aggressive and therefore does not affect the molecules previously printed on the surface. The array and the particles contained therein offer great versatility in both chemical and/or biological applications.

Consejo Superior de Investigaciones Científicas (España), Universidad de Barcelona

B1 Patente sin examen previo

Peer reviewed

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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