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DIGITAL.CSIC
Doctoral thesis . 2015 . Peer-reviewed
Data sources: DIGITAL.CSIC
ResearchGate Data
Thesis . 2016
Data sources: Datacite
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Estudio del mecanismo molecular de apoptosis y de la seguridad de la terapia fototérmica aplicada al tratamiento del cáncer utilizando nanoprismas de oro funcionalizados

Authors: Pérez-Hernández, Marta;

Estudio del mecanismo molecular de apoptosis y de la seguridad de la terapia fototérmica aplicada al tratamiento del cáncer utilizando nanoprismas de oro funcionalizados

Abstract

En esta tesis se ha descrito el uso de nanoprismas de oro para de forma eficiente y selectiva inducir apoptosis en celulas tumorales y mas importante, descifrar el mecanismo de muerte celular que se desencadena, para poder predecir la eficacia de la terapia fototermica usando nanoprismas de oro contra celulas tumorales que son resistentes a las terpias convencionales. Ademas se ha llevado a cabo un estudio en detalle de la toxicidad de los nanoprismas de oro in vitro asi como de su toxicidad y biodistribución in vivo para poder prevenir y minimizar posibles efectos adversos.

Tesis llevada a cabo para conseguir el grado de doctor en la Universidad de Zaragoza en enero de 2016.-- Sobresaliente "Cum Laude".

Peer reviewed

Country
Spain
Related Organizations
Keywords

Terapia fototérmica, Nanoprismas oro, Apoptosis, Toxicidad, Seguridad

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    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green