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Neuronal microprobe and method for the manufacture thereof

Authors: Villa, Rosa; Prats Alfonso, Elisabet; Gabriel Buguna, Gemma; Godignon, Philippe; Sánchez-Vives, María V.;

Neuronal microprobe and method for the manufacture thereof

Abstract

[ES] Procedimiento de fabricación de al menos una micro-sonda neuronal flexible, biocompatible e implantable, que comprender las etapas de: proporcionar una capa de un sustrato rígido (100); proporcionar una capa de un polímero soluble (110) sobre dicha capa de sustrato rígido; proporcionar una capa de un primer polímero (130); grabar en dicha capa de primer polímero al menos una abertura (151; 152); proporcionar una capa de un material conductor bidimensional (160) sobre dicha capa de primer polímero; grabar en dicha capa de material conductor bidimensional al menos un microelectrodo provisto de al menos un área de contacto; proporcionar un ensamblaje de acabado (195) sobre microelectrodo; y disolver dicho polímero soluble en una solución (120). El microelectrodo resultante (160) queda intercalado entre dos capas de material polimérico (190, 195), una de las cuales comprende una abertura (151; 152) para acceder a dicha área de contacto.

[EN] Method for manufacturing at least one flexible, biocompatible and implantable neuronal microprobe, which comprises the steps of: providing a rigid substrate layer (100); providing a soluble polymer layer (110) on said rigid substrate layer; providing a first polymer layer (130); etching at least one opening (151; 152) in said first polymer layer; providing a two-dimensional conductive layer (160) on said first polymer layer; etching at least one microelectrode having at least one contact area in said two-dimensional conductive layer; providing a finishing assembly (195) on the microelectrode; and dissolving said soluble polymer in a solution (120). The resulting microelectrode (160) is sandwiched between two polymer layers (190, 195), one of which comprises an opening (151; 152) for accessing said contact area.

Consejo Superior de Investigaciones Científicas, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Institució Catalana de Recerca i Estudis Avançats

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green